The first Yonkers death, of an unidentified man took place on Friday, Sept. 20, the second, of another unidentified man, happened on Saturday, Sept. 21, said Yonkers Police Det. Sgt. Dean Politopoulos.
The three others took place in the Woodlawn area of the Bronx, Politopoulos said.
Police believe all the cases may be related to the same source of cocaine.
The Yonkers Police Major Case Squad and Narcotics Unit, in collaboration with the NYPD and local law enforcement resources, are actively investigating these deaths and working to identify and apprehend the people responsible for distributing this apparent deadly substance, Politopoulos said.
"Community members are advised never to ingest unknown or un-prescribed controlled substances, especially illegal street drugs – the results can be fatal," he added.
Anyone with information regarding these incidents is asked to call the Yonkers Police Narcotics Unit at (914) 377-TIPS (8477).
All calls may remain anonymous and confidential.
Click here to follow Daily Voice Monsey and receive free news updates.